Research Units

Research Units

Pharmacokinetics Unit

The Pharmacokinetics (PK) unit is responsible for conducting in vivo and in vitro pharmacokinetics studies to evaluate preclinical drug candidates. The PK unit generates plasma concentration-time profiles from rodent and non-human primate models and calculates PK parameters such as plasma half-life, clearance, etc. The PK unit is also responsible for establishing and optimizing assays to determine antibody and antigen PK parameters of a wide variety of targets. A strong emphasis is made on developing assays that are robust, highly sensitive, and accurate. In addition to in vivo, in vitro studies and assay development, the PK unit also performs computational modelling and simulation of PK parameters.